Which of the following is most likely to be found on urinalysis?

Morning Quiz ☕

A 57-year-old man presents to the hospital with the following symptoms:

  • Nausea and vomiting

  • Severe cramping pain in the right flank

  • Additional History:

  • No fever or chills

  • Similar, but milder, pain occurred a few days ago and resolved spontaneously

Medical History:

  • Type 2 diabetes mellitus

  • Obesity

  • Hyperlipidemia

  • Hypertension

  • Gout

Vital Signs:

  • Temperature: 37°C (98.6°F)

  • Blood pressure: 160/100 mm Hg

  • Pulse: 98/min

Physical Examination:

  • Right flank tenderness

Laboratory Findings:

  • Blood urea nitrogen (BUN): Normal

  • Serum creatinine: Normal

Imaging Findings (Abdominal Ultrasound):

  • Right-sided hydronephrosis

  • Proximal ureteral dilation

Question:
Based on this presentation, which of the following is most likely to be found on urinalysis?

Options:
A. Malignant cells
B. Red blood cells
C. Red blood cell casts
D. Specific gravity of 1.002
E. White blood cell casts

Correct Answer 🎯: B. Red Blood Cells

⚙️

🧠 Obesity + Hyperlipidemia + Hypertension + Type 2 Diabetes Mellitus



↑ Risk of uric acid stone formation (gout history) and calcium oxalate stones (obesity, hyperlipidemia, diabetes)



Metabolic Dysregulation → ↑ Uric acid and calcium excretion in urine


🧠 Hyperuricemia + Hypercalciuria + Dehydration (if present)



Crystallization in the renal tubules or collecting system


Nephrolithiasis (kidney stone formation)

(think of a “clogged pipe 🚰” in the urinary system)


🧠 Stone moves from renal pelvis to ureter


Obstruction of the right ureter (proximal ureteral dilation on ultrasound)


Hydronephrosis (right-sided, as seen on ultrasound)

(“balloon inflating 🎈”)


🧠 Ureteral obstruction


Intraluminal pressure in the renal pelvis and ureter


Stretching of the renal capsule and ureter
(like “stretching a rubber band 🎗️”)


Severe crampy right flank pain (renal colic)


🧠 Obstruction + Stretching


Activation of renal afferent nerves


Nausea and vomiting (visceral autonomic response)


🧠 Mechanical trauma from the stone


Damage to urothelium


Hematuria (red blood cells in urine) → Correct Answer: B. Red Blood Cells

(like “scratches on a wall 🪨”)

⚖️ Differential Table

Differential ⚖️

Mechanism ⚙️

Why Incorrect? 🔴

Pyelonephritis

Bacterial infection of the kidney causing WBC casts, fever, and flank pain.

No fever, chills, or WBC casts on urinalysis.

Glomerulonephritis

Immune-mediated glomerular injury causing RBC casts, proteinuria, and edema.

No proteinuria, hypertension, or edema; RBC casts absent.

Urinary Tract Infection

Bacterial infection in the bladder or urethra causing dysuria and WBCs

No dysuria, fever, or WBCs in urine.

Diabetes Insipidus

Inability to concentrate urine, leading to dilute urine (specific gravity ⬇).

Patient is likely dehydrated; specific gravity would be high, not low.

📝 Flashcards

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