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After This ECG, Which of The Following is the Next Best Management ?
A 65-year-old man with a history of hypertension and coronary artery disease presents to the emergency department with a 2-hour history of severe chest pain radiating to his left arm. The pain began suddenly while he was resting. He describes it as a crushing sensation, 9/10 in intensity, and is associated with nausea and diaphoresis. His medications include aspirin, metoprolol, lisinopril, and atorvastatin. On arrival, his blood pressure is 90/60 mmHg, heart rate is 50/min, respiratory rate is 20/min, and oxygen saturation is 94% on room air. Physical examination reveals cool, clammy skin and distant heart sounds. An ECG shows 2 mm ST elevation in leads II, III, and aVF.
Which of the following is the most appropriate initial management step for this patient?
A) Administer intravenous nitroglycerin
B) Start high-dose atorvastatin
C) Perform immediate pericardiocentesis
D) Administer intravenous fluids
E) Give intravenous beta-blockers
Answer: D) Administer intravenous fluids
🧠 Summary:
Inferior MI with RVI → ⬇️ right ventricular output → ⬇️ preload to left heart → systemic hypotension.
IV Fluids ↑ preload and improve cardiac output.
RCA Occlusion → Inferior MI
🧠 Key Insight: RCA supplies right ventricle + inferior wall.
⬇️
Right Ventricular Infarction (RVI)
🧠 Right ventricular contractility ↓ (↓ pumping ability).
⬇️
↓ Right Ventricular Output
🧠 Key Insight: Right ventricle can't pump blood into pulmonary circulation.
⬇️
↓ Preload to Left Ventricle
🧠 Key Insight: Less blood to left ventricle from lungs → ↓ left-sided cardiac output.
⬇️
Systemic Hypotension
🧠 Key Insight: BP ↓ (systemic blood flow ↓).
⬇️
Bradycardia (often seen)
🧠 RCA also supplies SA node → conduction issues.
⬇️
Compensatory Mechanism
Vasoconstriction (cool, clammy skin) to maintain BP
⬇️
Corrective Management: IV Fluids (Answer D)
🧠 Key Insight: IV fluids ↑ preload to restore right ventricular function → ↑ cardiac output → BP ↑.

Why Other Options are Incorrect:
A) IV Nitroglycerin
🧠 Nitroglycerin ↓ preload → worsens hypotension due to further reduction in right ventricular filling.
B) High-dose Atorvastatin
🧠 Statins help long-term by stabilizing plaques, but don’t address acute hypotension.
C) Pericardiocentesis
🧠 No evidence of pericardial effusion or tamponade; heart sounds distant due to low cardiac output, not fluid.
E) IV Beta-blockers
🧠 Beta-blockers ↓ HR and contractility, further ↓ BP, worsening shock.
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